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Effect of Phytochemicals From Theobroma Cacao on Mental Energy

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala
Ingia / Ingia
Kiungo kimehifadhiwa kwenye clipboard
HaliImekamilika
Wadhamini
University of Georgia
Washirika
The Hershey Company

Maneno muhimu

Kikemikali

The purpose of this study is to determine which substances in cocoa produces changes in mental energy. This is a double blind study. The primary outcome measures are performance on tasks of sustained attention (serial subtract, continuous performance test and Bakan task) at pre and 90, 120 and 160 minutes post intervention, energy and fatigue symptoms (profile of mood state), and ratings of motivation to perform cognitive tasks. The assigned interventions are the following:

Maelezo

Only one prior study has examined the acute influence of cocoa on mental energy. The purpose of this research is to replicate the previous observations and extend research in four ways: 1) start to determine which substance in cocoa responsible for the effect by including several comparison groups, 2) focus on individuals with average or below average symptoms of mental energy and who are not high consumers of fruits, vegetables and other products containing high amounts of flavonoids in order to learn whether people with low energy accrue a greater benefit, and 3) include additional measures of mental energy plausibly influenced by cocoa to better understand the health consequences of cocoa.

Tarehe

Imethibitishwa Mwisho: 05/31/2018
Iliyowasilishwa Kwanza: 07/24/2012
Uandikishaji uliokadiriwa Uliwasilishwa: 07/25/2012
Iliyotumwa Kwanza: 07/26/2012
Sasisho la Mwisho Liliwasilishwa: 06/19/2018
Sasisho la Mwisho Lilichapishwa: 06/24/2018
Tarehe ya matokeo ya kwanza yaliyowasilishwa: 01/18/2017
Tarehe ya matokeo ya kwanza ya QC yaliyowasilishwa: 06/19/2018
Tarehe ya matokeo ya kwanza kuchapishwa: 06/24/2018
Tarehe halisi ya kuanza kwa masomo: 06/30/2012
Tarehe ya Kukamilisha Msingi iliyokadiriwa: 05/31/2014
Tarehe ya Kukamilisha Utafiti: 05/31/2014

Hali au ugonjwa

Mental Fatigue

Uingiliaji / matibabu

Other: Caffeinated cocoa

Other: Cocoa

Other: Caffeine

Other: Placebo

Awamu

-

Vikundi vya Arm

MkonoUingiliaji / matibabu
Active Comparator: Caffeinated cocoa
High flavanol, high theobromine, high caffeine, single dose administration in hot water vehicle
Other: Caffeinated cocoa
70 mg caffeine, 179 mg theobromine, 499 mg flavanols, and 1 packet of Truvia sweetener
Active Comparator: Cocoa
High flavanol, high theobromine, low caffeine, single dose administration in hot water vehicle
Other: Cocoa
21 mg caffeine, 179 mg theobromine, 499 mg flavanols, and 1 packet of Truvia sweetener
Active Comparator: Caffeine
Low flavanol, low theobromine, high caffeine, single dose administration in hot water vehicle
Other: Caffeine
473 ml brewed water containing 66 mg caffeine, caramel coloring and one packet Truvia sweetener
Placebo Comparator: Placebo
No flavanol, no theobromine, no caffeine, single dose administration in hot water vehicle
Other: Placebo
473 ml of brewed water, caramel coloring and one packet Truvia sweetener

Vigezo vya Kustahiki

Zama zinazostahiki Kujifunza 18 Years Kwa 18 Years
Jinsia Inastahiki KujifunzaAll
Hupokea Wajitolea wa AfyaNdio
Vigezo

Inclusion Criteria:

- Women and men ages 18-34

- Lower than average feelings of energy (score of < 13 on Profile of Mood States Vigor scale)

Exclusion Criteria:

- Pregnant

- GI tract disorder

- Psychoactive medication use

- Daily consumption of > 200 mg caffeine

- Body mass index > 30

- Cigarette smoker

- Allergy to cocoa, chocolate or caffeine

- Frequent consumption of cocoa, chocolate-based products or fruits and vegetable containing flavonoids

Matokeo

Hatua za Matokeo ya Msingi

1. Correct Responses on Serial 7 Subtraction Task [Pre and 30, 60 and 120 minutes post intervention]

Participants subtract the number 7 from a three digit number and quickly and accurately as possible for 60 seconds. The total number of accurate responses is scored. The higher the score the better performance. The range of scores is from a minimum score of 0 to a theoretical maximum score of 120.

2. Performance on Bakan Task [baseline, post 60, post 90, post 120]

Performance on Bakan Task at baseline, post-test 1, post-test 2, and post-test 3 Bakan test presents numbers on a computer screen. Participant presses one button whenever the number 6 appears and a different button whenever three odd and different numbers in a row occurs such as 7 5 9. The number of times the participant does this correctly the better the performance. The scores range from 0 to 10 because the sequence of three odd and different numbers occurs a total of 10 times.

Hatua za Matokeo ya Sekondari

1. Vigor Symptoms (Profile of Mood State) [Pre and 90, 120 and 160 minutes post intervention]

Vigor subscale scores from the Profile of Mood States.The higher the score the greater the feelings of energy. The scores range from a minimum of 0 to a maximum of 20.

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