paris/抗真菌药

Three steroidal saponins, including one new and two known compounds, were isolated from the rhizomes of Paris polyphylla Smith. One- and two-dimensional NMR, LC-MS, and interpretation of hydrolytic cleavage experiments led to the identification of the structure of the new saponin as (

BACKGROUND Scytalidium dimidiatum and S hyalinum are molds responsible for human skin and nail infections in tropical areas. OBJECTIVE We sought to examine the epidemiology of cutaneous infections caused by Scytalidium species in a temperate country. METHODS We conducted a retrospective study of

OBJECTIVE Sudden cardiac death (SCD) is a major public health concern, but data regarding epidemiology of this disease in Western European countries are outdated. This study reports the first results from a large registry of SCD. METHODS A population-based registry was established in May 2011 using

The French public-private partnerships known as "competitive clusters" [pôles de compétitivité (PdC)] are intended to be novel and ambitious engines of regional growth, employment and biomedical innovation. Partly funded by government and local councils, they aim to capitalize on regional expertise

Tremendous strides have been made in proteogenomics and RNA interference technologies. Hence "personalized" cancer gene therapy has become a foreseeable rather than a predictable reality. Currently, the lack of an optimized, systemic gene delivery vehicle remains a key limiting factor for developing

The number of cases of imported malaria diagnosed by the Parasitology Laboratory of the Pitié-Salpêtrière Hospital Group in Paris has shown a significant increase in recent years. From 1970 to 1979, 443 cases were diagnosed and the annual number recorded during this period rose from seven to 93

Treatment options for patients with pancreatic ductal adenocarcinoma (PDAC) remain limited. Therapeutic targets of interest include mutated molecules that predispose to pancreatic cancer such as KRAS and TP53. Here, we show that an element of the homologous recombination pathway of DNA repair, the

METHODS Analyze characteristics of neuromeningeal tuberculosis in the northeastern suburbs of Paris. METHODS Retrospective study of 19 observations between 1988 and 1999. RESULTS Thirteen cases of meningitis, 3 cases of meningitis associated with a tuberculoma and 3 cases with isolated tuberculoma

The authors report 427 cases of strongyloidasis detected in Paris, and emphasize the following points: --High incidence amongst black africans coming from West Africa (17%) ana black carribeans living in France (28.5%). --Lack of hypereosinophilia in two third of cases. --High incidence of

Pressure sores are one of the preferred nursing research topics but, in spite of the large number of studies, most questions related to the prevention and treatment of pressure sores remain unanswered. Well designed clinical trials and on sufficiently large samples are very rare and most treatments