uva-ursi/melanin

Effects of 50% methanolic extract (U-ext) from the leaf of Arctostaphylos uva-ursi (L.) Spreng. (bearberry leaf) on melanin synthesis were investigated in vitro. The U-ext and arbutin isolated from the bearberry leaf had an inhibitory effect on tyrosinase activity. Furthermore, the U-ext inhibited

OBJECTIVE To report a case of bilateral bull's-eye maculopathy in a patient who ingested uva ursi, a known inhibitor of melanin synthesis, for 3 years before the onset of symptoms. METHODS Observational case report. METHODS Both eyes of a female patient were examined in the clinical practice