giant/inflammation

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Biomarkers in Giant Cells Arteritis

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Ingia / Ingia

Polymyalgia Rheumatica and Giant Cell Arteritis

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Ingia / Ingia

Introduction: Polymyalgia Rheumatica (PMR) and Giant Cell Arteritis (GCA) are common inflammatory conditions. The diagnosis of PMR/GCA poses many challenges since there are no specific diagnostic tests. Recent literature emphasizes the ability of 18F-Fluorodeoxyglucose Positron Emission

Baricitinib in Relapsing Giant Cell Arteritis

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Ingia / Ingia

Baricitinib, an orally administered, potent, selective and reversible inhibitor of JAK1 and JAK2 has shown preliminary safety and efficacy in chronic, immune-mediated inflammatory conditions such as rheumatoid arthritis and psoriasis. This small molecule is uniquely suited as a potential novel

Giant Cell Arteritis: Improving Use of Ultrasound Evaluation

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Ingia / Ingia

Objectives and Project Plan: - Project Purpose: The purpose of the project is to develop the technology to reliably acquire and analyse ultrasound images through the use of a training programme which are comparable to those from scanning by an expert sonographer in the diagnosis (i.e. as a

Study of Circulating Microparticles in Giant Cell Arteritis

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Ingia / Ingia

PET Imaging of Giant Cell and Takayasu Arteritis

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Ingia / Ingia

Up-regulation of SST2 in activated macrophages represents a novel imaging target for measuring vascular inflammation, which has been previously examined in atherosclerosis using 68Ga-DOTATATE. To test the hypothesis that SST2 PET imaging can accurately identify LVV, patients with active GCA or

Giant Cell Arteritis and PET Scan (GAPS) Study

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Ingia / Ingia

Carotid Artery Neovascularization in Takayasu's and Giant Cell Arteritis

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Ingia / Ingia

Takayasu's arteritis and Giant Cell arteritis are chronic, relapsing diseases of the large arteries which can lead to significant narrowing of the arteries through episodes of inflammation within the artery walls. The changes in the vessel walls will be determined by an ultrasound test looking at

Determining Disease Activity Biomarkers in Individuals With Giant Cell Arteritis

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Ingia / Ingia

GCA is a rare autoimmune disorder and is the most common type of inflammation of medium- to large-sized blood vessels in the body. It usually only occurs in older adults. The most common symptoms of GCA include headache, pain in the shoulders and hips (polymyalgia rheumatica), pain in the jaw (jaw

Abatacept for Treating Adults With Giant Cell Arteritis and Takayasu's Arteritis

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Ingia / Ingia

GCA and TAK both cause inflammation in the lining of the arteries, which can interfere with the body's ability to carry oxygen to areas that need it. Symptoms of GCA include headaches, jaw pain, and blurred or double vision. Serious symptoms that occur less commonly are blindness and stroke. TAK

Ustekinumab for the Treatment of Relapse of Refractory Giant Cell Arteritis

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Ingia / Ingia

Clinical and Immunogenetic Characterization of Giant Cell Arteritis (GCA) and Polymyalgia Rheumatica (PMR)

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Ingia / Ingia

Giant cell arteritis (GCA), also known as temporal arteritis, is the most common form of primary systemic vasculitis, with up to 75,000 cases a year identified in the EU and US. It occurs almost exclusively in people over the age of 50 years and is considered to be a medical emergency. If not

Chewing Gum Test for the Diagnosis of Giant Cell Arteritis (Horton's Disease) - ChewingHort

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Ingia / Ingia

GCA is the most common vasculitis. The diagnosis easily could be made in patients over 50 years old with headache, inflammatory belt pain, claudication of the jaws, scalp hyperesthesia, ophthalmological manifestations and an inflammatory syndrome. However, the clinical pictures could be less

Use of Gallium-68 HA-DOTATATE PET/CT in Giant Cell Arteritis (GCA)

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Ingia / Ingia

The aim of this study is to prospectively evaluate the potential use of 68-Ga HA-DOTATATE PET/CT for detecting medium-large vessel inflammation in a small number of GCA patients with active disease, as compared to FDG PET/CT, and to understand if DOTATATE uptake correlates with disease activity.

MEthotrexate Versus TOcilizumab for Treatment of GIant Cell Arteritis: a Multicenter, Randomized, Controlled Trial

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Ingia / Ingia

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